16 September 2026 editorial review · Item
CiPSC-derived autologous islets (RGB-5088): review notes
These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.
Read the item evidence page →Preventing and curing evidence review — 16 September 2026
- Disposition: corrected/updated. Current item
lastReviewed: 2026-09-16. - Claim check: The published CiPSC recipient achieved insulin independence while already immunosuppressed; registry endpoints are not results. Removed the false claim that Sana treated the only human ever to carry an insulin-producing graft without drugs. Autologous origin does not establish protection from recurrent autoimmunity.
- Registry NCT06731218: RECRUITING; updated 2025-09-15; enrollment 10 (ESTIMATED); primary completion 2027-12-31 (ESTIMATED); results not posted in retrieved record.
- Registry NCT07464119: NOT_YET_RECRUITING; updated 2026-03-11; enrollment 30 (ESTIMATED); primary completion 2028-12-31 (ESTIMATED); results not posted in retrieved record.
- Primary publication/regulatory sources checked or consulted: j.cell.2024.09.004; 09636897251366828.