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16 September 2026 editorial review · Item

Denosumab beta-cell preservation: review notes

These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.

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Preventing and curing evidence review — 16 September 2026

  • Disposition: reviewed; no confirmed content change. Current item lastReviewed: 2026-08-27.
  • Claim check: Denosumab's registry requires residual C-peptide and has adult sex-specific age bands. No reported T1D benefit was located. Approval for bone disease does not establish a diabetes indication.
  • Registry NCT06524960: RECRUITING; updated 2026-07-28; enrollment 45 (ESTIMATED); primary completion 2027-10-11 (ESTIMATED); results not posted in retrieved record.

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