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16 September 2026 editorial review · Item

Fr1da (German General-Population T1D Screening): review notes

These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.

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Preventing and curing evidence review — 16 September 2026

  • Disposition: corrected/updated. Current item lastReviewed: 2026-09-16.
  • Claim check: JAMA 2026 cohort 220,476, five-year progression 36.2% and no family-history difference checked. Corrected initial DKA denominator: 280 screen-positive children were not 280 clinical diabetes diagnoses. No programme-wide near-zero-risk guarantee.
  • Registry NCT04039945: RECRUITING; updated 2024-12-17; enrollment 285000 (ESTIMATED); primary completion 2028-12 (ESTIMATED); results not posted in retrieved record.
  • Primary publication/regulatory sources checked or consulted: jama.2026.6085.

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