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16 September 2026 editorial review · Item

PLEDGE (Sanford general-population screening): review notes

These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.

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Preventing and curing evidence review — 16 September 2026

  • Disposition: reviewed; no confirmed content change. Current item lastReviewed: 2026-08-27.
  • Claim check: PLEDGE official study pages support Sanford footprint, research/free offer and coupled genetic/antibody approach. No published outcome upgrade or universal US availability inferred.
  • Registry NCT04477928: RECRUITING; updated 2026-03-02; enrollment 33000 (ESTIMATED); primary completion 2031-03 (ESTIMATED); results not posted in retrieved record.
  • Programme/sponsor/conference source boundary: PLEDGE Pediatric Screening Study (manufacturer).

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