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16 September 2026 editorial review · Item

Sorafenib for recent-onset T1D: review notes

These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.

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Preventing and curing evidence review — 16 September 2026

  • Disposition: new record; substantive review 16 September 2026.
  • Scope and findings: Added a narrow repurposing entry. Checked trial status, target 10, adult eligibility, insulin continuation and dates; current Bayer-hosted US label supports known drug warnings and cancer indications.
  • Primary sources checked: NCT06227221 — study record (registry); Nexavar (sorafenib) US prescribing information, revised August 2023 (regulatory).
  • Limits: Registry still not yet recruiting despite passed estimated start. No T1D benefit or safety outcomes. Selective immune mechanism is not asserted; category is editorial grouping.

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