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16 September 2026 editorial review · Trial

Hybrid closed-loop effectiveness in adults: review notes

These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.

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Baseline trial evidence review: A–H

Outcome: Expanded sparse summary/eligibility using current registry design, inclusion criteria and primary outcome; no efficacy inferred from registration.

Registry: NCT06236607. Registered endpoint checked: Glucose time-in-range (TIR) of 70-180 mg/dL (baseline, 39 weeks). Eligibility check: Registry age 18 Years to 75 Years; substantive diagnosis/stage, device and other inclusion restrictions were compared with the public eligibility summary. The registry remains the source for full exclusions. Limits: No usable primary abstract was independently recovered in this pass for this record. Protocol/design wording was assessed; any existing detailed sponsor, conference or historical outcome claims require their cited source and were not independently certified through full-text review.

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