16 September 2026 editorial review · Trial
OHSU closed-loop crossover: insulin alone vs insulin plus pramlintide: review notes
These notes document the scope actually reviewed, including source-access limits. They are not independent clinical certification or a guarantee that every claim was verified.
Read the trial evidence page →Baseline trial evidence review: M–S
Outcome: Reviewed actualpostedresults, added31participant firstmeal primary adjustedAUC benefit and nonsignificant TIR, distinguished adjusted vsraw means and acute vsfree-living; removedroadmaplinks.
Registry: NCT06422325. Endpoint reviewed: Incremental Area Under the Curve of Postprandial Glucose Following the First Meal (6 hours following first meal); Percent of Time With Sensed Glucose Between 70 - 180 mg/dl Following First Meal (6 hours following first meal). Eligibility reviewed: Age 18 Years to 70 Years; diagnosis/stage, prior therapy and key biomarker criteria compared with site summary. Full exclusions remain in the registry. Results access: Actual posted primary/secondary outcome tables were read, including denominator, group labels and estimates. No peer-reviewed status is inferred from posting.